The old 'What videogames made you cry' question.

[Minionman]

But not just limited to that genre.  The final cutscenes in 'Starcraft' still gets my heart tugging.  But cutscenes aside, I did feel a calm before a crap storm type of anticipation, during one of the missions where I had to hold a base from a zerg invasion.
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Also have reactions to starcraft. The end of brood war actually got me depressed for a day when I saw what it was.

The frozen throne single player also hits my emotions, I'm not sure how to describe it though. The night elf missions get me expecting something big to happen and drop me back down when it doesn't, the blood elf missions pull me in and make me feel as if I'm going crazy (the music helps a lot with this), the undead missions bring me back out of the mood of the blood elf missions, but also leave me slightly empty when nothign big happens and Arthas and Illidan get more cut off from the main part of the world. In the orc campaign I don't feel it matters much, and it goes from regular chores feeling to slightly exciting feeling. Those are sort of the feelings I go through.

The wierd part is the school year after frozen throne came out, I went through similar feelings in the same order throughout the school year, and the summer was similar to the orc campaign.

for gameplay moments, I used to get extremely on edge when fighting Diablo. I jumped back once in the chair when a spell came shooting into the screen when I wasn't expecting it.