Hey!

[Kasreyn]

Do you mean a new character? That doesn't make sense. All new characters start with an item or two (things like a short sword or buckler).

Or do you mean casting those aside and playing naked? In which case your only option in D2 is Sorceress, Necro, Singing Barb, or Hammerdin (I can't think of any viable way to play a nude Amazon); of course, Druid and Assassin may have capabilities for nude play, or not; I don't know one way or the other.

So I guess what I'm trying to say is, I don't know what you mean by "starting with no items". Are you used to starting new characters and twinking them heavily? If so, I'd advise you try the game without twinking. It's pretty fun, and even a little challenging, that way. =P

-Kasreyn