Back when I was 21/8/22, Preparation was in between Blind and Stealth while Cold Blood was in place of Blade Flurry. The simple idea is direct attack skills on bottom, other skills on top. I have the BottomRight bar in use, but I typically only had my assist macros there and my combat log slightly off to the side, so it covers about 8 of the 12 buttoms. The first three buttons are hotkeyed to 'R', 'T', and 'Y' for easy assisting while fighting. Bottom bar uses standard keys, top bar uses Ctrl+1 to Ctrl+=. Sidebar has no keybindings.
If you're wondering about my rant in there, it's something I have to do more testing about. After respecing and getting a new item, I went from +3% hit and +11 daggers to +9% to hit and +11 daggers. My melee miss rate went from about 23/24% to 22.2%. Another Rogue I've talked to has +10% to hit and a typical miss rate of 17% in MC/BWL ...
Trade yourself in for the perfect one. No one needs to know that you feel you've been ruined!