Wolfman

[Wyrm]

2. What is the best method/equipment (Merc?) for dealing with PIs?

The cold damage on a HF merc will very gradually take down PIs. Rabies and Fire Claws should do well enough. Anything to give you amp will help too.

3. How do I handle the Chaos Sanctuary/monsters who have IM as a curse?

Same way every other melee build does. Get a ranged char to help you out (Javazons work wonders). Or, if you're using a Buriza for a weapon, you can just use that untransformed.