Venomous WhirlWind Assassin

[Wyrm]

Never tried it personally, mainly because I'll probably never get the runes together to try it, but it sounds like it would work. The Venom duration is such that you'll probably be able to hit an enemy twice with it in one WW. The problem is the same as every other build that uses Venom, you have virtually no duration, and thus have a problem with monster HP regeneration in Hell.