The "blunt" class (which includes staves and wands) works with mace mastery, so yes, a barbarian CAN use mace mastery and benefit from it when using wands (and staves). Good luck and have fun :)
Edit: Actually, there are two things the barb cant master even considering this - bow/xbow and daggers.
Edit: Actually, there are two things the barb cant master even considering this - bow/xbow and daggers.