Debuff limit will be changed to 16 in patch 1.7

[Kevin]

If it were possible, with her present health, it would be around a 5 to 6 minute fight.

128k from CoDs barring no resists
58k from Corruptions every minute
40k from Life Siphons every minute

226k every minute from no resists and she has around 900k to 1 Million Health depending (slightly more, slightly less).
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And with 40 locks you could have imps whipping fireballs at her (I don't think she is fire immune, if she is then 24 succubus, keeping 2 imps per group in case one gets munched, are still going to help add some damage) and some of the locks could be slinging shadow bolts at her in the middle of the kiting as well, you wouldn't all be injured and needing to heal yourselves. That many locks would make the whelps pretty trivial if they showed up as well. Everyone would be soulstoned so everyone could die once as well and come right back up.