Teron Gorefiend Simulator

[Skandranon]

Does one person missing a ghost or ghosts on Teron Gorefiend automatically lead to a wipe however?

Near enough to such that it doesn't matter in my view. Shadowy Constructs do massive melee damage and pulse shadow damage that combines in a nasty way with Teron's Crushing Shadows debuff. Perhaps one construct escaping at low health might be survivable, barely, but keep in mind it's near a full thirty seconds before a follow-up competent ghost handler can get back there to polish it off, since they have to handle their own constructs without assistance, first. It's an awful lot of damage and Doom Blossoms plus even one Construct is multiple unavoidable deaths, usually of healers.

Obviously, if your first ghost handler nails their ghosts, the task becomes exponentially easier for people following up. In that sense, you could even say that Teron only has a single point of failure.